Treatment for HTLV-I associated arthropathy: a case study and synovial tissue culture analysis

  title={Treatment for HTLV-I associated arthropathy: a case study and synovial tissue culture analysis},
  author={Toshiaki Takahashi and Shigeki Takemoto and Katsuhito Kiyasu and Hiroshi Yamamoto and Toshikazu Tani and Isamu Miyoshi and Hirokuni Taguchi and Toshiaki Moriki and Emiko Miyazaki and Hideaki Enzan},
  journal={Rheumatology International},
Objective: There are few reports regarding the treatment of HTLV-I associated arthropathy (HAAP). This is a case study describing the treatment of a patient diagnosed with HAAP. We also analyzed the effects of various agents on cultured synovial tissue explants from the patient. Methods: Arthroscopic synovectomy of the left knee was performed. We investigated the effects of pirarubicin (THP), bestatin, betamethasone, and hyaluronic acid (HA) in synovial tissue culture to evaluate the efficacy… CONTINUE READING


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