Treatment for Charcot-Marie-Tooth disease.

  title={Treatment for Charcot-Marie-Tooth disease.},
  author={Peter Young and Peter de Jonghe and Florian Stoegbauer and Trude Butterfass-Bahloul},
  journal={The Cochrane database of systematic reviews},
BACKGROUND Charcot-Marie-Tooth disease (CMT) comprises a large variety of different forms of motor and sensory neuropathies. The most frequent are demyelinating forms (CMT1) and axonal forms (CMT2). The molecular basis of several CMT forms has been clarified during the last 15 years. Since muscle wasting and sensory disturbance are the main features of these syndromes, treatments aim to improve motor impairment and sensory disturbances. Specific treatment trials are rare. OBJECTIVES The… CONTINUE READING
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