• DOI:10.1212/WNL.0b013e3182050388
Corpus ID: 362182

Treatment effects of immunomodulatory therapies at different stages of multiple sclerosis in short-term trials

@article{Bates2011TreatmentEO,
  title={Treatment effects of immunomodulatory therapies at different stages of multiple sclerosis in short-term trials},
  author={D. Bates},
  journal={Neurology},
  year={2011},
  volume={76},
  pages={S14 - S25}
}

D. Bates

Published 2011

Medicine

Neurology

Intervention with interferon-β (IFNβ) therapy counters early inflammatory damage to myelin and protects axons; such therapy might demonstrate greater efficacy earlier in the disease course compared with later when permanent damage has already occurred. Clinical trials conducted in patients with clinically isolated syndrome (CIS) show clinical benefits of early treatment of multiple sclerosis (MS), as evidenced by delayed conversion to clinically definite multiple sclerosis and reduced… CONTINUE READING

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