Treatment effects of alprazolam and imipramine: physiological versus subjective changes in patients with generalized anxiety disorder.

@article{Mcleod1990TreatmentEO,
  title={Treatment effects of alprazolam and imipramine: physiological versus subjective changes in patients with generalized anxiety disorder.},
  author={D R Mcleod and Rudolf Hoehn-Saric and Wesley D. Zimmerli and Errol B De Souza and Lawrence K. Oliver},
  journal={Biological psychiatry},
  year={1990},
  volume={28 10},
  pages={849-61}
}
The correspondence between changes in physiological activity and somatic symptom reports was assessed in generalized anxiety disorder patients treated with alprazolam or imipramine. After 6 weeks, the two medications produced comparable reductions in self-reported somatic symptoms. However, patients taking alprazolam showed decreases in systolic blood pressure, epinephrine, and norepinephrine, and patients taking imipramine showed increases in heart rate, blood pressure, electromyographic… CONTINUE READING
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