Treatment and prophylaxis of cholera with bacteriophage.

  title={Treatment and prophylaxis of cholera with bacteriophage.},
  author={R M SAYAMOV},
  journal={Bulletin of the World Health Organization},
  volume={28 3},
  • Published 1963 in Bulletin of the World Health Organization
The treatment of cholera with bacteriophage has, in the past, been unsuccessful, owing to the fact that the phages prepared by the usual method (multiplication on cholera vibrios in broth) proved incapable of parasitizing cholera vibrios in vivo. In this paper, the author presents the results of therapeutic and prophylactic trials of a phage preparation prepared by a different method-namely, cultivation on cholera vibrios through alternate passages in the small intestine of guinea-pigs and in… CONTINUE READING