Treatment and health outcomes in adults with congenital adrenal hyperplasia

@article{Han2014TreatmentAH,
  title={Treatment and health outcomes in adults with congenital adrenal hyperplasia},
  author={T. S. Han and B. Walker and W. Arlt and R. Ross},
  journal={Nature Reviews Endocrinology},
  year={2014},
  volume={10},
  pages={115-124}
}
  • T. S. Han, B. Walker, +1 author R. Ross
  • Published 2014
  • Medicine
  • Nature Reviews Endocrinology
  • Congenital adrenal hyperplasia (CAH) is a genetic disorder caused by defective steroidogenesis that results in glucocorticoid deficiency; the most common underlying mutation is in the gene that encodes 21-hydroxylase. Life-saving glucocorticoid treatment was introduced in the 1950s, and the number of adult patients is now growing; however, no consensus has been reached on the management of CAH beyond childhood. Adult patients are prescribed a variety of glucocorticoids, including hydrocortisone… CONTINUE READING
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    References

    SHOWING 1-10 OF 104 REFERENCES
    Approach to the adult with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
    • D. Merke
    • Medicine
    • The Journal of clinical endocrinology and metabolism
    • 2008
    • 99
    • PDF
    Approach to the patient: the adult with congenital adrenal hyperplasia.
    • R. Auchus, W. Arlt
    • Medicine
    • The Journal of clinical endocrinology and metabolism
    • 2013
    • 73
    • PDF
    Effects of Adrenal Steroids on the Bone Metabolism of Children with Congenital Adrenal Hyperplasia
    • K. Lin-Su, M. New
    • Biology, Medicine
    • Annals of the New York Academy of Sciences
    • 2007
    • 11
    Congenital adrenal hyperplasia
    • 360
    Health Problems in Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
    • 90
    Clinical characteristics of a cohort of 244 patients with congenital adrenal hyperplasia.
    • 163
    • PDF
    Outcome of congenital adrenal hyperplasia
    • 71