Treatment and health outcomes in adults with congenital adrenal hyperplasia

@article{Han2014TreatmentAH,
  title={Treatment and health outcomes in adults with congenital adrenal hyperplasia},
  author={Thang Sieu Han and Brian R. Walker and Wiebke Arlt and Richard J Ross},
  journal={Nature Reviews Endocrinology},
  year={2014},
  volume={10},
  pages={115-124}
}
Congenital adrenal hyperplasia (CAH) is a genetic disorder caused by defective steroidogenesis that results in glucocorticoid deficiency; the most common underlying mutation is in the gene that encodes 21-hydroxylase. Life-saving glucocorticoid treatment was introduced in the 1950s, and the number of adult patients is now growing; however, no consensus has been reached on the management of CAH beyond childhood. Adult patients are prescribed a variety of glucocorticoids, including hydrocortisone… 
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