Treatment and follow-up strategies in hereditary nonpolyposis colorectal carcinoma.

@article{Mecklin1993TreatmentAF,
  title={Treatment and follow-up strategies in hereditary nonpolyposis colorectal carcinoma.},
  author={Jukka-Pekka Mecklin and Heikki J{\"a}rvinen},
  journal={Diseases of the colon and rectum},
  year={1993},
  volume={36 10},
  pages={927-9}
}
The treatment and follow-up strategies of patients with hereditary nonpolyposis colorectal carcinoma (HNPCC) were analyzed in 22 Finnish HNPCC families in systematic follow-up between 1983 and 1990. During the seven-year study period metachronous colorectal neoplasia was diagnosed in 41 percent (15/37) of the patients treated by segmental colonic resection and in 24 percent (4/17) of those treated by subtotal colectomy. Extracolonic carcinoma was diagnosed in 12 (30 percent) of the 40 patients… CONTINUE READING

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