• Corpus ID: 171087612

Treatment Effects of Fenugreek ( Trigonella foenum-graecum ) Seed Powder against High Calorie Diet Indused Obesity in Rats

  title={Treatment Effects of Fenugreek ( Trigonella foenum-graecum ) Seed Powder against High Calorie Diet Indused Obesity in Rats},
  author={Victoria Konopelniuk},
Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems. WHO estimates traditional medicines, mostly plant drugs cater to the health needs of nearly 80% of world population. The aim was to study the influence of Trigonella foenum-graecum seed powder on the basic parameters of obesity induced by hight calorie diet. We included 40 male rats and divided… 

Nutritional and Sensory Properties of Flat Bread Made from Fenugreek Seeds and Rice Bran and Its Effect on Hypercholesterolemic Rats

The resurgence of food-related chronic diseases has become a public health problem. The main target of the present research was to investigate the utilize of germinated fenugreek seeds (GFS) and



Hypoglycemic and antioxidative effects of fenugreek and termis seeds powder in streptozotocin-diabetic rats.

The data suggest that F, T and M seeds powder supplementation may be beneficial for preventing diabetic complications in this animal model.

Trigonella foenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic and lipogenic enzymes

The therapeutic role of Trigonella seed powder in type1 diabetes as exemplified in this study can be attributed to the change of glucose and lipid metabolising enzyme activities to normal values, thus stabilizing glucose homeostasis in the liver and kidney.

Diosgenin, the main aglycon of fenugreek, inhibits LXRα activity in HepG2 cells and decreases plasma and hepatic triglycerides in obese diabetic mice.

It is suggested that fenugreek ameliorates dyslipidemia by decreasing the hepatic lipid content in diabetic mice and that its effect is mediated by diosgenin.

Pharmacological effects of Trigonella foenum-graecum L. in health and disease

The resarch on Trigonella exhibits its health benefits and potential medicinal properties in various indications and has little or no side effects, suggesting its pharmaceutical, therapeutic and nutritional potential.

Effects of sodium-orthovanadate andTrigonella foenum-graecum seeds on hepatic and renal lipogenic enzymes and lipid profile during alloxan diabetes

Combined treatment of SOV and TSP with lower dose of TSP prevented the development of hyperglycemia and alteration in lipid profile in plasma and tissues and maintained it near normal.

The effect of an ethanol extract derived from fenugreek (Trigonella foenum-graecum) on bile acid absorption and cholesterol levels in rats

Results indicate that the ethanol extract from fenugreek seeds contained hypocholesterolaemic components which appear to be saponins that interact with bile salts in the digestive tract.

4-Hydroxyisoleucine from Fenugreek (Trigonella foenum-graecum): Effects on Insulin Resistance Associated with Obesity

4-Hydroxyisoleucine, a peculiar nonprotein amino acid isolated from fenugreek (Trigonella foenum-graecum) seeds, exhibits interesting effects on IR related to obesity, and the research regarding the insulinotropic and insulin-sensitising activity of 4-OHIle is presented.

Vitamin E regulates adipocytokine expression in a rat model of dietary-induced obesity

Administration of VE decreases leptin and adiponectin expression in obese rats, consistent with the view that antioxidants can play an important role in the treatment of obesity-related diseases.