Treating ulcerative colitis by Adacolumn therapeutic leucocytapheresis: clinical efficacy and safety based on surveillance of 656 patients in 53 centres in Japan.

@article{Hibi2009TreatingUC,
  title={Treating ulcerative colitis by Adacolumn therapeutic leucocytapheresis: clinical efficacy and safety based on surveillance of 656 patients in 53 centres in Japan.},
  author={Toshifumi Hibi and Yuichi Sameshima and Yukio Sekiguchi and Y Hisatome and Fumio Maruyama and Kensuke Moriwaki and Chikako Shima and Abby R. Saniabadi and Takayuki Matsumoto},
  journal={Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver},
  year={2009},
  volume={41 8},
  pages={570-7}
}
BACKGROUND/AIM The Adacolumn selectively depletes granulocytes and monocytes/macrophages, which are thought to be part of the immunopathogenesis of ulcerative colitis. This work aims at evaluating the safety and clinical efficacy of the Adacolumn in patients with ulcerative colitis in large population-based data sets. METHODS The Adacolumn post marketing surveillance in Japan was undertaken on 697 patients in 53 medical institutions over 7 years from 29 October 1999 to 28 October 2006… CONTINUE READING

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