Treating multiple sclerosis with monoclonal antibodies: a 2013 update.

  title={Treating multiple sclerosis with monoclonal antibodies: a 2013 update.},
  author={Annika Dei\ss and Isabel Brecht and Axel Haarmann and Mathias Buttmann},
  journal={Expert review of neurotherapeutics},
  volume={13 3},
The third part of this in-depth review series on the treatment of multiple sclerosis (MS) with monoclonal antibodies covers the years 2010-2012. The natalizumab section gives a progressive multifocal leukoencephalopathy update, focusing on clinically relevant aspects. Furthermore, it outlines problems around natalizumab cessation and current evidence on therapeutic strategies thereafter. Finally, it reviews evidence on Janus-faced modes of natalizumab action besides anti-inflammatory effects… CONTINUE READING
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