Treating cancer with microRNA replacement therapy: A literature review

@article{Hosseinahli2018TreatingCW,
  title={Treating cancer with microRNA replacement therapy: A literature review},
  author={Nayer Hosseinahli and M. Aghapour and Pascal H. G. Duijf and B. Baradaran},
  journal={Journal of Cellular Physiology},
  year={2018},
  volume={233},
  pages={5574 - 5588}
}
microRNAs (miRNAs) are small non‐coding RNAs that regulate gene expression post‐transcriptionally by interfering with the translation of one or more target mRNAs. The unique miRNA sequences are involved in many physiological and pathological processes. Dysregulation of miRNAs contributes to the pathogenesis of all types of cancer. Notably, the diminished expression of tumor suppressor miRNAs, such as members of the Let‐7 and miR‐34 family, promotes tumor progression, invasion and metastasis… Expand
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