Treating anemia early in renal failure patients slows the decline of renal function: a randomized controlled trial.

@article{Gouva2004TreatingAE,
  title={Treating anemia early in renal failure patients slows the decline of renal function: a randomized controlled trial.},
  author={Chariclia Gouva and Petros M. Nikolopoulos and John P. A. Ioannidis and Kostas Siamopoulos},
  journal={Kidney international},
  year={2004},
  volume={66 2},
  pages={753-60}
}
BACKGROUND Erythropoietin is known to improve outcomes in patients with anemia from chronic renal disease. However, there is uncertainty about the optimal timing of initiation of erythropoietin treatment in predialysis patients with non-severe anemia. METHODS We conducted a randomized controlled trial of early versus deferred initiation of erythropoietin in nondiabetic predialysis patients with serum creatinine 2 to 6 mg/dL and hemoglobin 9 to 11.6 g/dL. The early treatment arm was… CONTINUE READING

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