Treating Working Memory Deficits in Schizophrenia: A Review of the Neurobiology

@article{Lett2014TreatingWM,
  title={Treating Working Memory Deficits in Schizophrenia: A Review of the Neurobiology},
  author={Tristram A. Lett and Aristotle N. Voineskos and James L Kennedy and Brian Levine and Zafiris Jeff Daskalakis},
  journal={Biological Psychiatry},
  year={2014},
  volume={75},
  pages={361-370}
}
Cognitive deficits are a core feature of schizophrenia. Among these deficits, working memory impairment is considered a central cognitive impairment in schizophrenia. The prefrontal cortex, a region critical for working memory performance, has been demonstrated as a critical liability region in schizophrenia. As yet, there are no standardized treatment options for working memory deficits in schizophrenia. In this review, we summarize the neuronal basis for working memory impairment in… CONTINUE READING

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