Treating Alzheimer’s disease with monoclonal antibodies: current status and outlook for the future

In the past decade, Alzheimer’s disease drug discovery has been directed at ‘disease modifying drugs’ that are able to counteract the progression of Alzheimer’s disease by intervening in specific parts of its neuropathological process. Passive immunization with monoclonal antibodies (mAbs) may be able to clear toxic amyloid-β species either directly or… (More)