Treating AIDS-associated cerebral toxoplasmosis - pyrimethamine plus sulfadiazine compared with cotrimoxazole, and outcome with adjunctive glucocorticoids.

@article{Arens2007TreatingAC,
  title={Treating AIDS-associated cerebral toxoplasmosis - pyrimethamine plus sulfadiazine compared with cotrimoxazole, and outcome with adjunctive glucocorticoids.},
  author={James Arens and Karen Barnes and Nicola R Crowley and Gary Maartens},
  journal={South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde},
  year={2007},
  volume={97 10},
  pages={956-8}
}
We conducted a retrospective study of AIDS-associated cerebral toxoplasmosis. Eighteen patients received pyrimethamine plus sulfadiazine and 25 co-trimoxazole, with comparable baseline characteristics. There were no differences in clinical outcomes, but co-trimoxazole was better tolerated (p = 0.066). There was also a trend towards more deaths among patients who received glucocorticoids. 

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Steroids in neuroinfection.

Arquivos de neuro-psiquiatria • 2013

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International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases • 2010

Toxoplasmosis in HIV/AIDS: a living legacy.

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