Treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus.

@article{Kim2010TreadmillEP,
  title={Treadmill exercise prevents aging-induced failure of memory through an increase in neurogenesis and suppression of apoptosis in rat hippocampus.},
  author={Sung Eun Kim and Il-Gyu Ko and Bo-Kyun Kim and M N Shin and Sehyung Cho and C -K Kim and Sang-Hun Kim and Seung-Soo Baek and Eun-Kyu Lee and Yong-Seok Jee},
  journal={Experimental gerontology},
  year={2010},
  volume={45 5},
  pages={357-65}
}
Aging leads to functional changes in the hippocampus, and consequently induces cognitive deficits, such as failure of memory. Neurogenesis in the hippocampal dentate gyrus continues throughout life, but steadily declines from early adulthood. Apoptosis occurs under various pathologic and physiologic conditions, and excessive apoptotic cell death can cause a number of functional disorders in humans. Apoptosis in the hippocampus also disturbs cognitive functions. In this study, we examined the… CONTINUE READING
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