Treadmill exercise and wheel exercise enhance expressions of neutrophic factors in the hippocampus of lipopolysaccharide-injected rats.

@article{Kim2013TreadmillEA,
  title={Treadmill exercise and wheel exercise enhance expressions of neutrophic factors in the hippocampus of lipopolysaccharide-injected rats.},
  author={Sung Eun Kim and Il-Gyu Ko and M N Shin and C -K Kim and Byung-Kwan Jin and Hoon-Pyo Hong and Yong-Seok Jee},
  journal={Neuroscience letters},
  year={2013},
  volume={538},
  pages={54-9}
}
Brain inflammation plays a pivotal role in the pathogenesis of chronic neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. We investigated the effects of treadmill exercise and wheel exercise on spatial learning ability in relation with long-term potentiation (LTP) using lipopolysaccharide-induced brain inflammation in the rats. Brain inflammation was induced by an injection of LPS into the cerebral ventricle. We found that brain inflammation impaired spatial… CONTINUE READING
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