Treadmill Exercise Improves Fracture Toughness and Indentation Modulus without Altering the Nanoscale Morphology of Collagen in Mice

@article{Hammond2016TreadmillEI,
  title={Treadmill Exercise Improves Fracture Toughness and Indentation Modulus without Altering the Nanoscale Morphology of Collagen in Mice},
  author={Max A. Hammond and Tyler J Laine and Alycia G. Berman and J. Wallace},
  journal={PLoS ONE},
  year={2016},
  volume={11}
}
  • Max A. Hammond, Tyler J Laine, +1 author J. Wallace
  • Published 2016
  • Medicine, Chemistry, Materials Science
  • PLoS ONE
  • The specifics of how the nanoscale properties of collagen (e.g., the crosslinking profile) affect the mechanical integrity of bone at larger length scales is poorly understood despite growing evidence that collagen’s nanoscale properties are altered with disease. Additionally, mass independent increases in postyield displacement due to exercise suggest loading-induced improvements in bone quality associated with collagen. To test whether disease-induced reductions in bone quality driven by… CONTINUE READING

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