Treadmill Exercise Improves Fracture Toughness and Indentation Modulus without Altering the Nanoscale Morphology of Collagen in Mice

@inproceedings{Hammond2016TreadmillEI,
  title={Treadmill Exercise Improves Fracture Toughness and Indentation Modulus without Altering the Nanoscale Morphology of Collagen in Mice},
  author={Max A. Hammond and Tyler J Laine and Alycia G. Berman and Joseph M Wallace},
  booktitle={PloS one},
  year={2016}
}
The specifics of how the nanoscale properties of collagen (e.g., the crosslinking profile) affect the mechanical integrity of bone at larger length scales is poorly understood despite growing evidence that collagen's nanoscale properties are altered with disease. Additionally, mass independent increases in postyield displacement due to exercise suggest loading-induced improvements in bone quality associated with collagen. To test whether disease-induced reductions in bone quality driven by… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Bone fracture toughness and strength correlate with collagen cross-link maturity in a dose-controlled lathyrism mouse model.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research • 2015

Circadian regulation of bone metabolism by βadrenergic signaling , glucocorticoids , and clock genes

H Kondo, A Togari
J Oral Biosci • 2015

Similar Papers

Loading similar papers…