Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study

@inproceedings{Calandre2011TrazodonePP,
  title={Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study},
  author={Elena P Calandre and Piedad Morillas-Arques and Roc{\'i}o Molina-Barea and Carmen Mar{\'i}a Rodr{\'i}guez-L{\'o}pez and Fernando Rico-Villademoros},
  booktitle={BMC musculoskeletal disorders},
  year={2011}
}
BACKGROUND Although trazodone is frequently used by fibromyalgia patients, its efficacy on this disease has not been adequately studied. If effective, pregabalin, whose beneficial effects on pain and sleep quality in fibromyalgia have been demonstrated, could complement the antidepressant and anxiolytic effects of trazodone. The aim of the present study was to assess the effectiveness of trazodone alone and in combination with pregabalin in the treatment of fibromyalgia. METHODS This was an… CONTINUE READING
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