Traversing the Cell: Agrobacterium T-DNA’s Journey to the Host Genome

@inproceedings{Gelvin2012TraversingTC,
  title={Traversing the Cell: Agrobacterium T-DNA’s Journey to the Host Genome},
  author={Stanton B Gelvin},
  booktitle={Front. Plant Sci.},
  year={2012}
}
The genus Agrobacterium is unique in its ability to conduct interkingdom genetic exchange. Virulent Agrobacterium strains transfer single-strand forms of T-DNA (T-strands) and several Virulence effector proteins through a bacterial type IV secretion system into plant host cells. T-strands must traverse the plant wall and plasma membrane, traffic through the cytoplasm, enter the nucleus, and ultimately target host chromatin for stable integration. Because any DNA sequence placed between T-DNA… CONTINUE READING

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