Traumatic brain injury in mice and pentadecapeptide BPC 157 effect.

  title={Traumatic brain injury in mice and pentadecapeptide BPC 157 effect.},
  author={Mario Tudor and Ivan Jandri{\'c} and Anton Marovi{\'c} and Miroslav Gjura{\vs}in and Darko Perovi{\'c} and Bo{\vz}o Radi{\'c} and Alenka Boban Blagaic and Danijela Kolenc and Luka Br{\vc}i{\'c} and Kamelija Žarkovi{\'c} and Sven Seiwerth and P Sikiri{\'c}},
  journal={Regulatory peptides},
  volume={160 1-3},
Gastric pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, an anti-ulcer peptide, efficient in inflammatory bowel disease trials (PL 14736), no toxicity reported, improved muscle crush injury. After an induced traumatic brain injury (TBI) in mice by a falling weight, BPC 157 regimens (10.0microg, 10.0ng/kgi.p.) demonstrated a marked attenuation of damage with an improved early outcome and a minimal postponed mortality throughout a 24h post-injury period. Ultimately, the traumatic lesions… CONTINUE READING