Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+ homeostatic mechanisms in hippocampal neurons surviving brain injury.

@article{Sun2008TraumaticBI,
  title={Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+ homeostatic mechanisms in hippocampal neurons surviving brain injury.},
  author={David A Sun and Laxmikant S. Deshpande and Sompong Sombati and Anya Baranova and Margaret S Wilson and Robert J Hamm and Robert J Delorenzo},
  journal={The European journal of neuroscience},
  year={2008},
  volume={27 7},
  pages={1659-72}
}
Traumatic brain injury (TBI) survivors often suffer chronically from significant morbidity associated with cognitive deficits, behavioral difficulties and a post-traumatic syndrome and thus it is important to understand the pathophysiology of these long-term plasticity changes after TBI. Calcium (Ca2+) has been implicated in the pathophysiology of TBI-induced neuronal death and other forms of brain injury including stroke and status epilepticus. However, the potential role of long-term changes… CONTINUE READING