Traumatic brain injury in children.
- MedicineMissouri medicine
TBI has been referred to as the "silent epidemic" and is a major public health concern with significant long term sequellae.
Traumatic Brain Injury
- Medicine, Biology
In this chapter, the classification, pathophysiology, and critical care treatments now considered as best practices for the management of TBI are described.
Traumatic Head Injury
- Medicine, Biology
The primary aspects of TBI, including its epidemiology, mechanisms of injury, early management, monitoring, and prognosis, are reviewed.
Traumatic brain injury in children and adolescents.
- MedicineChild and adolescent psychiatric clinics of North America
Controversies in the Management of Traumatic Brain Injury.
- MedicineAnesthesiology clinics
Hypothermic protection in traumatic brain injury.
- MedicinePathophysiology : the official journal of the International Society for Pathophysiology
Clinical Outcomes after Traumatic Brain Injury
- MedicineCurrent Neurology and Neuroscience Reports
In this review, prognostic algorithms useful for clinicians are discussed and ongoing work focusing on the development of biomarkers to track TBI recovery and the refinement of clinical outcome metrics is summarized.
Outcome After Severe Traumatic Brain Injury (TBI)
Most of the long-term disability from TBI is caused by neurobehavioural problems (cognitive impairment, depression, anxiety and aggression) which constitute an important barrier to reentry to society.
Challenges During Surgery for Traumatic Brain Injury in Children and Adults
- MedicineEssentials of Neurosurgical Anesthesia & Critical Care
In 2008, approximately 230,000 people hospitalized for TBI will survive, which is not trivial since severe TBI carries a mortality of 30–50%, although deaths have declined because of improved treatments and systems for managing trauma.
Traumatic alterations in consciousness: traumatic brain injury.
- MedicineEmergency medicine clinics of North America
SHOWING 1-10 OF 99 REFERENCES
Severe head injury: prehospital and emergency department management.
- MedicineThe Mount Sinai journal of medicine, New York
Hyperventilation has been shown to decrease cerebral perfusion and should be avoided; it is a temporizing procedure that is reserved for those cases that demonstrate signs of increased intracranial pressure pending initiation of other therapies.
The role of secondary brain injury in determining outcome from severe head injury.
- MedicineThe Journal of trauma
The increased morbidity and mortality related to severe trauma to an extracranial organ system appeared primarily attributable to associated hypotension, and improvements in trauma care delivery over the past decade have not markedly altered the adverse influence of hypotension.
The outcome from severe head injury with early diagnosis and intensive management.
- Medicine, PsychologyJournal of neurosurgery
It is proposed that vigorous surgical and medical therapy, by preventing or reversing secondary cerebral insults, enables some patients who would have died to make a good recovery without increasing the proportion of severely disabled patients.
Delayed and progressive brain injury in closed-head trauma: radiological demonstration.
The importance of delayed or secondary brain insults in the eventual outcome of closed-head trauma has been documented in experimental models and the relationship between severity of injury, delayed insults, and outcome is explored.
The Westmead Head Injury Project outcome in severe head injury. A comparative analysis of pre-hospital, clinical and CT variables.
- MedicineBritish journal of neurosurgery
A prospective study of 315 consecutive patients with a severe head injury was undertaken to study factors contributing to mortality and morbidity, both in the pre-hospital and hospital phases. Entry…
Intracranial hypertension and cerebral perfusion pressure: Influence on neurological deterioration and outcome in severe head injury.:
Examination of the relationship and relative importance of ICP and CPP in severely head injured patients is examined by examining the higher risk group who manifest neurological deterioration following initial resuscitation after admission to the hospital.
Traumatic acute subdural hematoma: major mortality reduction in comatose patients treated within four hours.
- MedicineThe New England journal of medicine
The delay from injury to operation was the factor of greatest therapeutic importance, and patients who underwent surgery within the first four hours had a 30 per cent mortality rate, as compared with 90 percent in those who had surgery after four hours.
Enhanced vulnerability to secondary ischemic insults after experimental traumatic brain injury.
- MedicineNew horizons
Although numerous mediators may be involved in increased tissue sensitivity, those that particularly merit investigation include oxygen free radicals, glutamate, arachidonate metabolites, calcium ions, and protein kinase C.
Cerebral circulation and metabolism after severe traumatic brain injury: the elusive role of ischemia.
- MedicineJournal of neurosurgery
The results support the hypothesis that early ischemia after traumatic brain injury may be an important factor determining neurological outcome, and suggest that early hyperventilation or lowering of blood pressure to prevent brain edema may be harmful.