• Corpus ID: 161392490

Trattamento chirurgico del carcinoma midollare della tiroide. Esperienza personale

  title={Trattamento chirurgico del carcinoma midollare della tiroide. Esperienza personale},
  author={Girolamo Geraci and Franco Pisello and A Tornamb{\`e} and Lina Platia and Carmelo Scium{\`e} and F LiVolsi and Francesco Cupido and Giuseppe Modica},
  journal={Il Giornale di chirurgia},
Introduzione: il carcinoma midollare della tiroide (CMT) e una rara neoplasia delle cellule C o parafollicolari della tiroide. Scopo del nostro lavoro el'analisi retrospettiva della nostra esperienza sul trattamento del CMT con particolare attenzione al ruolo della linfoadenectomia. Pazienti e metodi: da gennaio 2000 a marzo 2006, sono state eseguite 546 tiroidectomie, 6 delle quali in pazienti con CMT (1.09%): 5 casi sporadici e 1 familiare. Tutti i pazienti sono stati sottoposti a… 
2 Citations
Calcitonin assay in wash-out fluid after fine-needle aspiration biopsy in patients with a thyroid nodule and border-line value of the hormone
Borderline CT values in patients with thyroid nodules are not rare and CT-FNAB does not have the same importance as that reported in the literature for thyroglobulin and PTH assay in wash-out fluid after FNAB in malignant thyroid and hyperfunctioning parathyroid lesions.


Natural history, diagnosis, treatment and outcome of medullary thyroid cancer: 37 years experience on 157 patients.
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    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
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Medullary thyroid carcinoma: state of the art.
A total thyroidectomy and vigilant management and surveillance of the neck are recommended and interdisciplinary management including surgeons, endocrinologists, pathologists, radiotherapists, radiologists, and oncologists should be considered.
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    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
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It is concluded that prophylactic thyroidectomy, based on direct DNA testing for RET gene mutations, is an effective and safe way to manage MTC in patients with MEN 2A.
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It is deemed it fundamental to perform total thyroidectomy in all advanced cases of thyroid neoplasm and to extend neoplasms excision to the adjacent tissues, even involving justified surgical demolition.
Optimal Surgery for Papillary Thyroid Carcinoma
The feasibility, scope, sample size, and length of follow-up required to determine the optimal operation for papillary thyroid carcinoma is analyzed and a cause-specific mortality trial proves to be the most objective and statistically valid endpoint.
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The resection of metastatic MCT to regional lymph nodes can be associated with appreciable survival, and prognostic parameters are identified that adversely affect survival.
Medullary carcinoma of the thyroid gland
The best chance of cure lies in early diagnosis through the use of immunoreactive calcitonin measurement in family members at risk, and an aggressive surgical attack on the primary tumor and any cervical metastases.
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MTCs are capable of synthesizing catecholamines, serotonin, and histamine metabolites underscoring that MTCs have metabolic characteristics in common with other neuroendocrine tumors.
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It is concluded that familial nonmultiple endocrine neoplasia medullary thyroid carcinoma, early medullaries thyroid carcinomas or C-cell hyperplasia, and asymptomatic patients have a good prognosis and total thyroidectomy and central neck clearance is the procedure of choice for Medullary Thyroid carcinoma.
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The susceptibility gene has been mapped but not isolated, and in some kindreds polymorphic markers that flank the gene can be used for predictive DNA testing.