• DOI:10.1097/00019605-199510000-00013
Corpus ID: 6330050

Transverse limb deficiency, facial clefting and hypoxic renal damage: an association with treatment of maternal hypertension?

@article{Hurst1995TransverseLD,
  title={Transverse limb deficiency, facial clefting and hypoxic renal damage: an association with treatment of maternal hypertension?},
  author={J. Hurst and R. Houlston and A. Roberts and S. Gould and W. G. Tingey},
  journal={Clinical Dysmorphology},
  year={1995},
  volume={4},
  pages={359–363}
}

J. Hurst, R. Houlston, +2 authors W. G. Tingey

Published 1995

Medicine

Clinical Dysmorphology

View on Wolters Kluwer

ncbi.nlm.nih.gov

Save to Library

Create Alert

Cite

Launch Research Feed

&NA; Transverse limb defects are reported in a fetus and an infant born to mothers on treatment for hypertension. One pregnancy resulted in an intrauterine death at 20 weeks, and in addition to the limb defects, there was bilateral cleft lip and palate and renal hypoxic damage. It is proposed that the drugs caused maternal hypotension which led to reduced uteroplacental blood flow, fetal hypotension and hypoxia and that the anomalies seen in the two babies are a consequence of these events.