Transvalencin Z, a New Antimicrobial Compound with Salicylic Acid Residue from Nocardia transvalensis IFM 10065
@article{Mukai2006TransvalencinZA, title={Transvalencin Z, a New Antimicrobial Compound with Salicylic Acid Residue from Nocardia transvalensis IFM 10065}, author={Akira Mukai and Toshio Fukai and Yuko Matsumoto and Jun Ishikawa and Yasutaka Hoshino and Katsukiyo Yazawa and Ken‐ichi Harada and Yuzuru Mikami}, journal={The Journal of Antibiotics}, year={2006}, volume={59}, pages={366-369} }
Transvalencin Z was isolated from a culture broth of Nocardia transvalensis IFM 10065, a clinical isolate from a Japanese patient with actinomycotic mycetoma. The transvalencin Z structure was determined using NMR and mass spectrometric analyses. The structure is similar to a partial structure of siderophores such as mycobactins and nocobactins, but the compound has no cytotoxic activity. Transvalencin Z shows a strong antimicrobial activity against Gram-positive bacteria, but shows no activity…
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