Transthyretin: a key gene involved in the maintenance of memory capacities during aging.

@article{Brouillette2008TransthyretinAK,
  title={Transthyretin: a key gene involved in the maintenance of memory capacities during aging.},
  author={Jonathan Brouillette and R{\'e}mi Quirion},
  journal={Neurobiology of aging},
  year={2008},
  volume={29 11},
  pages={1721-32}
}
Aging is often associated with decline of memory function. Aged animals, like humans, can naturally develop memory impairments and thus represent a useful model to investigate genes involved in long-term memory formation that are differentially expressed between aged memory-impaired (AI) and aged memory-unimpaired (AU) animals following stimulation in a spatial memory task. We found that alterations in hippocampal gene expression of transthyretin (TTR), calcineurin, and NAD(P)H dehydrogenase… CONTINUE READING

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