Transposon-mediated multiple antibiotic resistance in Acinetobacter strains.

  title={Transposon-mediated multiple antibiotic resistance in Acinetobacter strains.},
  author={M C Devaud and Fritz H. Kayser and Brigitte B{\"a}chi},
  journal={Antimicrobial agents and chemotherapy},
  volume={22 2},
Acinetobacter calcoaceticus subsp. anitratus, which is unusually resistant to multiple antibiotics, was the cause of an epidemic of respiratory tract infections in patients in an intensive care unit. A representative isolate of the epidemic strain was found to contain the aminoglycoside-modifying enzymes 3-N-acetyltransferase, 3'-phosphotransferase, and 3"-adenylyltransferase, which confer resistance to gentamicin, kanamycin, and streptomycin, respectively. In addition, the strain produced a… CONTINUE READING


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