Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes.

@article{Gordenin1992TransposonTE,
  title={Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes.},
  author={Dmitry A Gordenin and A L Malkova and A Peterzen and Vladimir N. Kulikov and Youri I. Pavlov and Edward W. Perkins and Michael Resnick},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1992},
  volume={89 9},
  pages={
          3785-9
        }
}
Interaction between short repeats may be a source of genomic rearrangements and deletions. We investigated possible interactions between short (9 base pairs) direct repeats in yeast by using our previously described system for analyzing bacterial transposon Tn5 excision in yeast. Mutations of either POL3 or POL1, the proposed structural genes for polymerases delta and alpha, respectively, yield high levels of excision at semipermissive temperatures. pol2 (corresponding to polymerase epsilon… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 19 CITATIONS

Similar Papers