Transposition of an antibiotic resistance element in mycobacteria

@article{Martn1990TranspositionOA,
  title={Transposition of an antibiotic resistance element in mycobacteria},
  author={Carlos Mart{\'i}n and Juliano Timm and Jean Rauzier and Rafael G{\'o}mez-Lus and Julian Davies and Brigitte Gicquel},
  journal={Nature},
  year={1990},
  volume={345},
  pages={739-743}
}
BACTERIAL resistance to antibiotics is often plasmid-mediated and the associated resistance genes encoded by transposable elements. Mycobacteria, including the human pathogens Mycobacterium tuberculosis and M. leprae, are resistant to many antibiotics, and their cell-surface structure is believed to be largely responsible for the wide range of resistance phenotypes. Antibiotic-resistance plasmids have so far not been implicated in resistance of mycobacteria to antibiotics. Nevertheless… CONTINUE READING

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