Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions

@inproceedings{Kelley2014TransposableEM,
  title={Transposable elements modulate human RNA abundance and splicing via specific RNA-protein interactions},
  author={David R Kelley and David G. Hendrickson and Danielle E. Tenen and John L Rinn},
  booktitle={Genome Biology},
  year={2014}
}
Transposable elements (TEs) have significantly influenced the evolution of transcriptional regulatory networks in the human genome. Post-transcriptional regulation of human genes by TE-derived sequences has been observed in specific contexts, but has yet to be systematically and comprehensively investigated. Here, we study a collection of 75 CLIP-Seq experiments mapping the RNA binding sites for a diverse set of 51 human proteins to explore the role of TEs in post-transcriptional regulation of… CONTINUE READING
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