Transposable element insertion location bias and the dynamics of gene drive in mosquito populations.

@article{Rasgon2005TransposableEI,
  title={Transposable element insertion location bias and the dynamics of gene drive in mosquito populations.},
  author={Jason L. Rasgon and Fred Gould},
  journal={Insect molecular biology},
  year={2005},
  volume={14 5},
  pages={493-500}
}
Some vector-borne disease control strategies using transgenic mosquitoes require transgene spread to high frequency in populations. Transposable elements (TEs) are DNA sequences that replicate and transpose within the genomes of other organisms and may therefore be represented in the next generation in higher frequencies than predicted by Mendelian segregation. This over-representation has allowed some TEs to spread through natural populations. Transgenes incorporated within a TE sequence are… CONTINUE READING