Transporters for cationic amino acids in animal cells: discovery, structure, and function.

@article{Devs1998TransportersFC,
  title={Transporters for cationic amino acids in animal cells: discovery, structure, and function.},
  author={Rosa Dev{\'e}s and C A Richard Boyd},
  journal={Physiological reviews},
  year={1998},
  volume={78 2},
  pages={487-545}
}
The structure and function of the four cationic amino acid transporters identified in animal cells are discussed. The systems differ in specificity, cation dependence, and physiological role. One of them, system y+, is selective for cationic amino acids, whereas the others (B[0,+], b[0,+], and y+ L) also accept neutral amino acids. In recent years, cDNA clones related to these activities have been isolated. Thus two families of proteins have been identified: 1) CAT or cationic amino acid… CONTINUE READING
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