Transport routes through the nuclear pore complex.

@article{Pemberton1998TransportRT,
  title={Transport routes through the nuclear pore complex.},
  author={Lucy F. Pemberton and Giinter Blobel and Jonathan S. Rosenblum},
  journal={Current opinion in cell biology},
  year={1998},
  volume={10 3},
  pages={392-9}
}
The nuclear pore complex can be considered to be the stationary phase of bidirectional traffic between the nucleus and the cytoplasm. The mobile phase consists of karyopherins, transport substrates, and the small GTPase Ran and its modulators. Recently, the family of karyopherins was expanded with the recognition of numerous open reading frames with limited homology to karyopherin beta 1. In several cases, the specific substrates transported by the new karyopherins have been identified… CONTINUE READING

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