Transport routes through the nuclear pore complex.

  title={Transport routes through the nuclear pore complex.},
  author={Lucy F. Pemberton and Giinter Blobel and Jonathan S. Rosenblum},
  journal={Current opinion in cell biology},
  volume={10 3},
The nuclear pore complex can be considered to be the stationary phase of bidirectional traffic between the nucleus and the cytoplasm. The mobile phase consists of karyopherins, transport substrates, and the small GTPase Ran and its modulators. Recently, the family of karyopherins was expanded with the recognition of numerous open reading frames with limited homology to karyopherin beta 1. In several cases, the specific substrates transported by the new karyopherins have been identified… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 74 extracted citations

Progress in utilizing nuclear localization signal peptides in gene transfer

YUAN Zhi-Dong, SHEN Xiao-Zhou, LI Jian-Fan, LIU Hai-Sheng
View 10 Excerpts
Highly Influenced

Nuclear transport: never-ending cycles of signals and receptors.

Essays in biochemistry • 2000
View 6 Excerpts
Highly Influenced

Protein nucleocytoplasmic transport and its light regulation in plants.

Genes to cells : devoted to molecular & cellular mechanisms • 1999
View 5 Excerpts
Highly Influenced

Nuclear-Cytoplasmic Transport

Nucleic Acids and Molecular Biology • 2018

Similar Papers

Loading similar papers…