Transport properties of the host cell membrane.

  title={Transport properties of the host cell membrane.},
  author={Kiaran Kirk and Henry M. Staines and Rowena E. Martin and Kevin J. Saliba},
  journal={Novartis Foundation symposium},
  pages={55-66; discussion 66-73}
The malaria-infected erythrocyte shows an increased permeability to a wide range of solutes. The increase is mediated in part by parasite-induced new permeation pathways (NPP) and in part (for some solutes, under some conditions) by increased activity of endogenous transporters. The NPP provide the major route for the influx into the infected cell of a number of essential nutrients, but although the functional characteristics of these pathways are understood in some detail, they are yet to be… CONTINUE READING