Transport of purine nucleotides and nucleosides by in vitro rabbit ileum.

Abstract

The kinetics of [14C]ATP and [14C]adenosine entry into rabbit ileum were measured using 1-min mucosal exposures. ATP influx was the sum of a linear (P = 1.02 X 10(-3) cm/min) and nonlinear component (Jm = 4.07 nmol/min cm2, Km = 0.31 mM). Adenosine yielded quantitatively similar results. The kinetics of [gamma-32P]ATP entry were only linear (P = 0.55 X 10… (More)

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