Transport of multidrug resistance substrates by the Streptococcus agalactiae hemolysin transporter.

@article{Gottschalk2006TransportOM,
  title={Transport of multidrug resistance substrates by the Streptococcus agalactiae hemolysin transporter.},
  author={Birgit Gottschalk and Gerd Br{\"o}ker and Melanie Kuhn and Simone Aymanns and Ute Gleich-Theurer and Barbara Spellerberg},
  journal={Journal of bacteriology},
  year={2006},
  volume={188 16},
  pages={5984-92}
}
Streptococcus agalactiae (group B streptococcus [GBS]) causes neonatal sepsis, pneumonia, and meningitis, as well as infections of the bovine udder. The S. agalactiae hemolysin is regarded as an important virulence factor, and hemolysin expression is dependent on the cyl gene cluster. cylA and cylB encode the ATP binding and transmembrane domains of a typical ATP binding cassette (ABC) transporter. The deduced proteins contain the signature sequence of a multidrug resistance (MDR) transporter… CONTINUE READING