Transport of molecules, particles, and cells in solid tumors.

  title={Transport of molecules, particles, and cells in solid tumors.},
  author={Rakesh K. Jain},
  journal={Annual review of biomedical engineering},
  • Rakesh K. Jain
  • Published 1999 in Annual review of biomedical engineering
Extraordinary advances in molecular biology and biotechnology have led to the development of a vast number of therapeutic anti-cancer agents. To reach cancer cells in a tumor, a blood-borne therapeutic molecule, particle, or cell must make its way into the blood vessels of the tumor and across the vessel wall into the interstitium, which it then must migrate through. Unfortunately, tumors often develop in ways that hinder these steps. The goal of research in this area is to analyze each of… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 238 extracted citations

Peptides as drug delivery vehicles across biological barriers

Journal of Pharmaceutical Investigation • 2017
View 6 Excerpts
Highly Influenced

Convection-enhanced drug delivery for gliomas

Surgical neurology international • 2015
View 6 Excerpts
Highly Influenced

Table of Content Editorial 4

View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…