Transport of molecules, particles, and cells in solid tumors.

@article{Jain1999TransportOM,
  title={Transport of molecules, particles, and cells in solid tumors.},
  author={Rakesh K. Jain},
  journal={Annual review of biomedical engineering},
  year={1999},
  volume={1},
  pages={241-63}
}
  • Rakesh K. Jain
  • Published 1999 in Annual review of biomedical engineering
Extraordinary advances in molecular biology and biotechnology have led to the development of a vast number of therapeutic anti-cancer agents. To reach cancer cells in a tumor, a blood-borne therapeutic molecule, particle, or cell must make its way into the blood vessels of the tumor and across the vessel wall into the interstitium, which it then must migrate through. Unfortunately, tumors often develop in ways that hinder these steps. The goal of research in this area is to analyze each of… CONTINUE READING
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