Transport of macromolecules across microvascular walls: the two-pore theory.

@article{Rippe1994TransportOM,
  title={Transport of macromolecules across microvascular walls: the two-pore theory.},
  author={Bengt Rippe and Boerje Haraldsson},
  journal={Physiological reviews},
  year={1994},
  volume={74 1},
  pages={
          163-219
        }
}
In this review we summarized the evidence favoring the concept that the major plasma proteins are passively transported across vascular walls through water-filled pathways by means of convection and diffusion. With regard to solute transport, a majority of microvascular walls seems to show a bimodal size selectivity. This implies the presence of a high frequency of functional small pores, restricting proteins, and an extremely low number of non-size-selective pathways, permitting the passage of… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 182 CITATIONS, ESTIMATED 53% COVERAGE

342 Citations

01020'95'00'06'12'18
Citations per Year
Semantic Scholar estimates that this publication has 342 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…