Transport of drugs across the blood-brain barrier by nanoparticles.


The central nervous system is well protected by the blood-brain barrier (BBB) which maintains its homeostasis. Due to this barrier many potential drugs for the treatment of diseases of the central nervous system (CNS) cannot reach the brain in sufficient concentrations. One possibility to deliver drugs to the CNS is the employment of polymeric nanoparticles… (More)
DOI: 10.1016/j.jconrel.2011.08.017


Cite this paper

@article{Wohlfart2012TransportOD, title={Transport of drugs across the blood-brain barrier by nanoparticles.}, author={Stefanie Wohlfart and Svetlana E. Gelperina and Joerg Kreuter}, journal={Journal of controlled release : official journal of the Controlled Release Society}, year={2012}, volume={161 2}, pages={264-73} }