Transport of choline in rat brain slices.

  title={Transport of choline in rat brain slices.},
  author={Qin Xin and R Mark Wightman},
  journal={Brain research},
  volume={776 1-2},
Enzyme-modified amperometric microsensors have been utilized in the investigation of acetylcholine and choline diffusion in solution and choline uptake and diffusion in rat brains. A small amount of the substance of interest was introduced by pressure injection and transport to the sensor was monitored. The apparent diffusion coefficients for acetylcholine and choline in agarose gel perfused with physiological solutions were determined to be 5.2 +/- 0.7 x 10(-6) cm2/s and 6.1 +/- 0.8 x 10(-6… CONTINUE READING

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