Transport of carbamazepine and drug interactions at blood-brain barrier

AbstractAim:To investigate the characteristics of carbamazepine (CBZ) transport and drug interactions at the blood-brain barrier.Methods:Cultured rat brain microvascular endothelial cells (rBMEC) were used as an in vitro model of the blood-brain barrier (BBB). When cells became confluent, CBZ uptake over time was recorded by incubation of the cells in a… (More)