Transport of bile acids in hepatic and non-hepatic tissues.

  title={Transport of bile acids in hepatic and non-hepatic tissues.},
  author={Marie V. St-Pierre and Gerd A Kullak-Ublick and Bruno Hagenbuch and Peter Meier},
  journal={The Journal of experimental biology},
  volume={204 Pt 10},
Bile acids are steroidal amphipathic molecules derived from the catabolism of cholesterol. They modulate bile flow and lipid secretion, are essential for the absorption of dietary fats and vitamins, and have been implicated in the regulation of all the key enzymes involved in cholesterol homeostasis. Bile acids recirculate through the liver, bile ducts, small intestine and portal vein to form an enterohepatic circuit. They exist as anions at physiological pH and, consequently, require a carrier… CONTINUE READING


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