Transport of Proteolytic Enzymes Across Caco-2 Cell Monolayers

Abstract

Purpose. To investigate the mechanisms by which proteolytic enzymes, such as trypsin, chymotrypsin, papain, and bromelain, are able to cross the intestinal mucosal barrier after oral administration to man. Methods. Filter-grown Caco-2 cell monolayers were incubated with proteolytic enzymes and then the transepithelial electrical resistance (TEER) and the… (More)
DOI: 10.1023/A:1011949521144

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