• DOI:10.1016/S0014-5793(01)03318-X
Corpus ID: 38836496

Transport of N‐acetyl‐D‐mannosamine and N‐acetyl‐D‐glucosamine in Escherichia coli K1: effect on capsular polysialic acid production

@article{RevillaNun2002TransportON,
  title={Transport of N‐acetyl‐D‐mannosamine and N‐acetyl‐D‐glucosamine in Escherichia coli K1: effect on capsular polysialic acid production},
  author={B. Revilla-Nu{\'i}n and {\'A}. Reglero and H. Mart{\'i}nez-Blanco and Ignacio G Bravo and Miguel A Ferrero and Leandro B Rodrı́guez-Aparicio},
  journal={FEBS Letters},
  year={2002},
  volume={511}
}

• B. Revilla-Nuín, Á. Reglero, +3 authors Leandro B Rodrı́guez-Aparicio
• Published 2002
• Chemistry, Medicine
• FEBS Letters

N‐Acetyl‐D‐mannosamine (ManNAc) and N‐acetyl‐D‐glucosamine (GlcNAc) are the essential precursors of N‐acetylneuraminic acid (NeuAc), the specific monomer of polysialic acid (PA), a bacterial pathogenic determinant. Escherichia coli K1 uses both amino sugars as carbon sources and uptake takes place through the mannose phosphotransferase system transporter, a phosphoenolpyruvate‐dependent phosphotransferase system that shows a broad range of specificity. Glucose, mannose, fructose, and… Expand