Transport of N‐acetyl‐D‐mannosamine and N‐acetyl‐D‐glucosamine in Escherichia coli K1: effect on capsular polysialic acid production

@article{RevillaNun2002TransportON,
  title={Transport of N‐acetyl‐D‐mannosamine and N‐acetyl‐D‐glucosamine in Escherichia coli K1: effect on capsular polysialic acid production},
  author={B. Revilla-Nu{\'i}n and {\'A}. Reglero and H. Mart{\'i}nez-Blanco and Ignacio G. Bravo and M. Ferrero and L. Rodr{\'i}guez-aparicio},
  journal={FEBS Letters},
  year={2002},
  volume={511}
}
  • B. Revilla-Nuín, Á. Reglero, +3 authors L. Rodríguez-aparicio
  • Published 2002
  • Chemistry, Medicine
  • FEBS Letters
  • N‐Acetyl‐D‐mannosamine (ManNAc) and N‐acetyl‐D‐glucosamine (GlcNAc) are the essential precursors of N‐acetylneuraminic acid (NeuAc), the specific monomer of polysialic acid (PA), a bacterial pathogenic determinant. Escherichia coli K1 uses both amino sugars as carbon sources and uptake takes place through the mannose phosphotransferase system transporter, a phosphoenolpyruvate‐dependent phosphotransferase system that shows a broad range of specificity. Glucose, mannose, fructose, and… CONTINUE READING
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