Transport of L-phenylalanine and related amino acids at the ovine blood-brain barrier.


1. Unidirectional influx of amino acids at the blood-brain barrier was studied in the lamb and sheep under barbiturate anaesthesia using the single-pass indicator-dilution technique. 2. In the lamb, influx of both L-phenylalanine (14 +/- 1 nmol g-1 min-1) and L-alanine (12 +/- 2 nmol g-1 min-1) was greater than in the sheep: L-phenylalanine influx, 9 +/- 1… (More)


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