Transport of Influenza HA from the trans-Golgi Network to the Apical Surface of MDCK Cells Permeabilized in their Basolateral Plasma Membranes: Energy Dependence and Involvement of GTP-binding Proteins

  • Diego Gravot, David D. Sabat
  • Published 1990

Abstract

A procedure employing streptolysin O to effect the selective permeabilization of either the apical or basolateral plasma membrane domains of MDCK cell monolayers grown on a filter support was developed which permeabilizes the entire monolayer, leaves the opposite cell surface domain intact, and does not abolish the integrity of the tight junctions. This… (More)

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11 Figures and Tables