Transport effects on surface-volume biological reactions.

  title={Transport effects on surface-volume biological reactions.},
  author={David A. Edwards and Byron Goldstein and Donald S. Cohen},
  journal={Journal of mathematical biology},
  volume={39 6},
Many cellular reactions involve a reactant in solution binding to or dissociating from a reactant confined to a surface. This is true as well for a BIAcore, an optical biosensor that is widely used to study the interaction of biomolecules. In the flow cell of this instrument, one of the reactants is immobilized on a flat sensor surface while the other reactant flows past the surface. Both diffusion and convection play important roles in bringing the reactants into contact. Usually BIAcore… CONTINUE READING