Transport and Utilization of Arginine and Arginine-Containing Peptides by Rat Alveolar Macrophages

Abstract

Purpose. To demonstrate that rat alveolar macrophages (AM) exhibited the PepT1-like transporter for the uptake of arginine (Arg)-containing small peptides and utilized these peptides as direct substrates for nitric oxide (NO) production. NO is an important mediator that, on one hand, protects the lung from bacteria infection and, on the other hand, augments… (More)
DOI: 10.1023/A:1016132200104

Topics

9 Figures and Tables

Cite this paper

@article{Yang2002TransportAU, title={Transport and Utilization of Arginine and Arginine-Containing Peptides by Rat Alveolar Macrophages}, author={Xiao-dong Yang and Jane Y. C. Ma and Mark W. Barger and Joseph K. H. Ma}, journal={Pharmaceutical Research}, year={2002}, volume={19}, pages={825-831} }