Transport, catabolism and release of histamine in the ruminal epithelium of sheep

@article{Aschenbach2000TransportCA,
  title={Transport, catabolism and release of histamine in the ruminal epithelium of sheep},
  author={J{\"o}rg R Aschenbach and Robby Oswald and Gotthold G{\"a}bel},
  journal={Pfl{\"u}gers Archiv},
  year={2000},
  volume={440},
  pages={171-178}
}
Whereas intraruminal histamine does not affect healthy ruminants, histaminosis is apparent during ruminal acidosis. We therefore investigated the factors that, under physiological circumstances, prevent intoxication by intraruminal histamine and the disturbances occurring during acidotic or hypoxic epithelial damage. After mucosal (m) or serosal (s) application of 80 µM histamine, its flux across the isolated epithelia of the sheep rumen was determined radioactively (hist-rad flux) in Ussing… CONTINUE READING
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